Atrius India Core FHIR Implementation Guide - Local Development build (v0.1.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
Resource Profile: Atrius India Core Substance
| Official URL: https://atrius.in/fhir/r4/atrius-in/StructureDefinition/atrius-in-substance | Version: 0.1.0 | ||||
| Draft as of 2026-07-24 | Computable Name: AtriusInSubstance | ||||
| Other Identifiers: OID:1.3.6.1.4.1.66219.1.42.111 | |||||
Atrius India Core profile. Parent: FHIR R4. Structurally aligned with QI-Core. India terminology via NDHM ValueSets where noted. Legacy QI-Core projection: runtime-mapper.
Usages:
- Refer to this Profile: Atrius India Core AdverseEvent and Atrius India Core Substance
You can also check for usages in the FHIR IG Statistics
Formal Views of Profile Content
Description Differentials, Snapshots, and other representations.
| Name | Flags | Card. | Type | Description & Constraints Filter:   |
|---|---|---|---|---|
  Substance |
0..* | Substance(4.0.1) | A homogeneous material with a definite composition | |
  implicitRules |
?!Σ | 0..1 | uri | A set of rules under which this content was created |
 modifierExtension |
?! | 0..* | Extension | Extensions that cannot be ignored Constraints: ext-1 |
| status |
?!SΣ | 0..1 | code | active | inactive | entered-in-error Binding: FHIRSubstanceStatus (required): A code to indicate if the substance is actively used. |
 code |
SΣ | 1..1 | CodeableConcept | What substance this is Binding: SubstanceCode (example): Substance codes. |
 instance |
SΣ | 0..* | BackboneElement | If this describes a specific package/container of the substance |
 modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized Constraints: ext-1 |
 quantity |
SΣ | 0..1 | SimpleQuantity(4.0.1) | Amount of substance in the package |
 ingredient |
SΣ | 0..* | BackboneElement | Composition information about the substance |
 modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized Constraints: ext-1 |
| quantity |
SΣ | 0..1 | Ratio | Optional amount (concentration) |
 Slices for substance[x] |
SΣ | 1..1 | A component of the substance Slice: Unordered, Open by type:$this Binding: SubstanceCode (example): Substance Ingredient codes. | |
 substanceCodeableConcept |
CodeableConcept | |||
 substanceReference |
Reference(Substance) | |||
  substance[x]:substanceReference |
SΣ | 0..1 | Reference(Atrius India Core Substance(0.1.0)) | A component of the substance |
| Documentation for this format | ||||
Terminology Bindings
| Path | Status | Usage | ValueSet | Version | Source |
| Substance.status | Base | required | FHIRSubstanceStatus | 📍4.0.1 | FHIR Std. |
| Substance.code | Base | example | Substance Code | 📍4.0.1 | FHIR Std. |
| Substance.ingredient.substance[x] | Base | example | Substance Code | 📍4.0.1 | FHIR Std. |
Constraints
| Id | Grade | Path(s) | Description | Expression |
| dom-2 | error | Substance | If the resource is contained in another resource, it SHALL NOT contain nested Resources |
contained.contained.empty()
|
| dom-3 | error | Substance | If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource |
contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
|
| dom-4 | error | Substance | If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated |
contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
|
| dom-5 | error | Substance | If a resource is contained in another resource, it SHALL NOT have a security label |
contained.meta.security.empty()
|
| dom-6 | best practice | Substance | A resource should have narrative for robust management |
text.`div`.exists()
|
| ele-1 | error | Substance.implicitRules, Substance.modifierExtension, Substance.status, Substance.code, Substance.instance, Substance.instance.modifierExtension, Substance.instance.quantity, Substance.ingredient, Substance.ingredient.modifierExtension, Substance.ingredient.quantity, Substance.ingredient.substance[x], Substance.ingredient.substance[x]:substanceReference | All FHIR elements must have a @value or children |
hasValue() or (children().count() > id.count())
|
| ext-1 | error | Substance.modifierExtension, Substance.instance.modifierExtension, Substance.ingredient.modifierExtension | Must have either extensions or value[x], not both |
extension.exists() != value.exists()
|
| Name | Flags | Card. | Type | Description & Constraints Filter: |
|---|---|---|---|---|
| Substance |
0..* | Substance(4.0.1) | A homogeneous material with a definite composition | |
 status |
S | 0..1 | code | active | inactive | entered-in-error |
| code |
S | 1..1 | CodeableConcept | What substance this is |
| instance |
S | 0..* | BackboneElement | If this describes a specific package/container of the substance |
| quantity |
S | 0..1 | SimpleQuantity(4.0.1) | Amount of substance in the package |
| ingredient |
S | 0..* | BackboneElement | Composition information about the substance |
| quantity |
S | 0..1 | Ratio | Optional amount (concentration) |
| Slices for substance[x] |
S | 1..1 | CodeableConcept, Reference(Substance) | A component of the substance Slice: Unordered, Open by type:$this |
| substance[x]:substanceReference |
S | 0..1 | Reference(Atrius India Core Substance(0.1.0)) | A component of the substance |
| Documentation for this format | ||||
| Name | Flags | Card. | Type | Description & Constraints Filter: | ||||
|---|---|---|---|---|---|---|---|---|
| Substance |
0..* | Substance(4.0.1) | A homogeneous material with a definite composition | |||||
| id |
Σ | 0..1 | id | Logical id of this artifact | ||||
| meta |
Σ | 0..1 | Meta | Metadata about the resource | ||||
| implicitRules |
?!Σ | 0..1 | uri | A set of rules under which this content was created | ||||
| language |
0..1 | code | Language of the resource content Binding: CommonLanguages (preferred): A human language.
| |||||
| text |
0..1 | Narrative | Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements | |||||
| contained |
0..* | Resource | Contained, inline Resources | |||||
 extension |
0..* | Extension | Additional content defined by implementations Constraints: ext-1 | |||||
| modifierExtension |
?! | 0..* | Extension | Extensions that cannot be ignored Constraints: ext-1 | ||||
| identifier |
Σ | 0..* | Identifier | Unique identifier | ||||
| status |
?!SΣ | 0..1 | code | active | inactive | entered-in-error Binding: FHIRSubstanceStatus (required): A code to indicate if the substance is actively used. | ||||
| category |
Σ | 0..* | CodeableConcept | What class/type of substance this is Binding: SubstanceCategoryCodes (extensible): Category or classification of substance. | ||||
| code |
SΣ | 1..1 | CodeableConcept | What substance this is Binding: SubstanceCode (example): Substance codes. | ||||
| description |
Σ | 0..1 | string | Textual description of the substance, comments | ||||
| instance |
SΣ | 0..* | BackboneElement | If this describes a specific package/container of the substance | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations Constraints: ext-1 | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized Constraints: ext-1 | ||||
| identifier |
Σ | 0..1 | Identifier | Identifier of the package/container | ||||
| expiry |
Σ | 0..1 | dateTime | When no longer valid to use | ||||
| quantity |
SΣ | 0..1 | SimpleQuantity(4.0.1) | Amount of substance in the package | ||||
| ingredient |
SΣ | 0..* | BackboneElement | Composition information about the substance | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations Constraints: ext-1 | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized Constraints: ext-1 | ||||
| quantity |
SΣ | 0..1 | Ratio | Optional amount (concentration) | ||||
| Slices for substance[x] |
SΣ | 1..1 | A component of the substance Slice: Unordered, Open by type:$this Binding: SubstanceCode (example): Substance Ingredient codes. | |||||
| substanceCodeableConcept |
CodeableConcept | |||||||
| substanceReference |
Reference(Substance) | |||||||
| substance[x]:substanceReference |
SΣ | 0..1 | Reference(Atrius India Core Substance(0.1.0)) | A component of the substance | ||||
| Documentation for this format | ||||||||
Terminology Bindings
| Path | Status | Usage | ValueSet | Version | Source |
| Substance.language | Base | preferred | Common Languages | 📍4.0.1 | FHIR Std. |
| Substance.status | Base | required | FHIRSubstanceStatus | 📍4.0.1 | FHIR Std. |
| Substance.category | Base | extensible | Substance Category Codes | 📍4.0.1 | FHIR Std. |
| Substance.code | Base | example | Substance Code | 📍4.0.1 | FHIR Std. |
| Substance.ingredient.substance[x] | Base | example | Substance Code | 📍4.0.1 | FHIR Std. |
Constraints
| Id | Grade | Path(s) | Description | Expression |
| dom-2 | error | Substance | If the resource is contained in another resource, it SHALL NOT contain nested Resources |
contained.contained.empty()
|
| dom-3 | error | Substance | If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource |
contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
|
| dom-4 | error | Substance | If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated |
contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
|
| dom-5 | error | Substance | If a resource is contained in another resource, it SHALL NOT have a security label |
contained.meta.security.empty()
|
| dom-6 | best practice | Substance | A resource should have narrative for robust management |
text.`div`.exists()
|
| ele-1 | error | Substance.meta, Substance.implicitRules, Substance.language, Substance.text, Substance.extension, Substance.modifierExtension, Substance.identifier, Substance.status, Substance.category, Substance.code, Substance.description, Substance.instance, Substance.instance.extension, Substance.instance.modifierExtension, Substance.instance.identifier, Substance.instance.expiry, Substance.instance.quantity, Substance.ingredient, Substance.ingredient.extension, Substance.ingredient.modifierExtension, Substance.ingredient.quantity, Substance.ingredient.substance[x], Substance.ingredient.substance[x]:substanceReference | All FHIR elements must have a @value or children |
hasValue() or (children().count() > id.count())
|
| ext-1 | error | Substance.extension, Substance.modifierExtension, Substance.instance.extension, Substance.instance.modifierExtension, Substance.ingredient.extension, Substance.ingredient.modifierExtension | Must have either extensions or value[x], not both |
extension.exists() != value.exists()
|
Summary
Must-Support: 8 elements
Structures
This structure refers to these other structures:
Slices
This structure defines the following Slices:
- The element 1 is sliced based on the value of Substance.ingredient.substance[x]
Key Elements View
| Name | Flags | Card. | Type | Description & Constraints Filter: |
|---|---|---|---|---|
| Substance |
0..* | Substance(4.0.1) | A homogeneous material with a definite composition | |
| implicitRules |
?!Σ | 0..1 | uri | A set of rules under which this content was created |
| modifierExtension |
?! | 0..* | Extension | Extensions that cannot be ignored Constraints: ext-1 |
| status |
?!SΣ | 0..1 | code | active | inactive | entered-in-error Binding: FHIRSubstanceStatus (required): A code to indicate if the substance is actively used. |
| code |
SΣ | 1..1 | CodeableConcept | What substance this is Binding: SubstanceCode (example): Substance codes. |
| instance |
SΣ | 0..* | BackboneElement | If this describes a specific package/container of the substance |
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized Constraints: ext-1 |
| quantity |
SΣ | 0..1 | SimpleQuantity(4.0.1) | Amount of substance in the package |
| ingredient |
SΣ | 0..* | BackboneElement | Composition information about the substance |
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized Constraints: ext-1 |
| quantity |
SΣ | 0..1 | Ratio | Optional amount (concentration) |
| Slices for substance[x] |
SΣ | 1..1 | A component of the substance Slice: Unordered, Open by type:$this Binding: SubstanceCode (example): Substance Ingredient codes. | |
| substanceCodeableConcept |
CodeableConcept | |||
| substanceReference |
Reference(Substance) | |||
| substance[x]:substanceReference |
SΣ | 0..1 | Reference(Atrius India Core Substance(0.1.0)) | A component of the substance |
| Documentation for this format | ||||
Terminology Bindings
| Path | Status | Usage | ValueSet | Version | Source |
| Substance.status | Base | required | FHIRSubstanceStatus | 📍4.0.1 | FHIR Std. |
| Substance.code | Base | example | Substance Code | 📍4.0.1 | FHIR Std. |
| Substance.ingredient.substance[x] | Base | example | Substance Code | 📍4.0.1 | FHIR Std. |
Constraints
| Id | Grade | Path(s) | Description | Expression |
| dom-2 | error | Substance | If the resource is contained in another resource, it SHALL NOT contain nested Resources |
contained.contained.empty()
|
| dom-3 | error | Substance | If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource |
contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
|
| dom-4 | error | Substance | If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated |
contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
|
| dom-5 | error | Substance | If a resource is contained in another resource, it SHALL NOT have a security label |
contained.meta.security.empty()
|
| dom-6 | best practice | Substance | A resource should have narrative for robust management |
text.`div`.exists()
|
| ele-1 | error | Substance.implicitRules, Substance.modifierExtension, Substance.status, Substance.code, Substance.instance, Substance.instance.modifierExtension, Substance.instance.quantity, Substance.ingredient, Substance.ingredient.modifierExtension, Substance.ingredient.quantity, Substance.ingredient.substance[x], Substance.ingredient.substance[x]:substanceReference | All FHIR elements must have a @value or children |
hasValue() or (children().count() > id.count())
|
| ext-1 | error | Substance.modifierExtension, Substance.instance.modifierExtension, Substance.ingredient.modifierExtension | Must have either extensions or value[x], not both |
extension.exists() != value.exists()
|
Differential View
| Name | Flags | Card. | Type | Description & Constraints Filter: |
|---|---|---|---|---|
| Substance |
0..* | Substance(4.0.1) | A homogeneous material with a definite composition | |
| status |
S | 0..1 | code | active | inactive | entered-in-error |
| code |
S | 1..1 | CodeableConcept | What substance this is |
| instance |
S | 0..* | BackboneElement | If this describes a specific package/container of the substance |
| quantity |
S | 0..1 | SimpleQuantity(4.0.1) | Amount of substance in the package |
| ingredient |
S | 0..* | BackboneElement | Composition information about the substance |
| quantity |
S | 0..1 | Ratio | Optional amount (concentration) |
| Slices for substance[x] |
S | 1..1 | CodeableConcept, Reference(Substance) | A component of the substance Slice: Unordered, Open by type:$this |
| substance[x]:substanceReference |
S | 0..1 | Reference(Atrius India Core Substance(0.1.0)) | A component of the substance |
| Documentation for this format | ||||
Snapshot ViewView
| Name | Flags | Card. | Type | Description & Constraints Filter: | ||||
|---|---|---|---|---|---|---|---|---|
| Substance |
0..* | Substance(4.0.1) | A homogeneous material with a definite composition | |||||
| id |
Σ | 0..1 | id | Logical id of this artifact | ||||
| meta |
Σ | 0..1 | Meta | Metadata about the resource | ||||
| implicitRules |
?!Σ | 0..1 | uri | A set of rules under which this content was created | ||||
| language |
0..1 | code | Language of the resource content Binding: CommonLanguages (preferred): A human language.
| |||||
| text |
0..1 | Narrative | Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements | |||||
| contained |
0..* | Resource | Contained, inline Resources | |||||
| extension |
0..* | Extension | Additional content defined by implementations Constraints: ext-1 | |||||
| modifierExtension |
?! | 0..* | Extension | Extensions that cannot be ignored Constraints: ext-1 | ||||
| identifier |
Σ | 0..* | Identifier | Unique identifier | ||||
| status |
?!SΣ | 0..1 | code | active | inactive | entered-in-error Binding: FHIRSubstanceStatus (required): A code to indicate if the substance is actively used. | ||||
| category |
Σ | 0..* | CodeableConcept | What class/type of substance this is Binding: SubstanceCategoryCodes (extensible): Category or classification of substance. | ||||
| code |
SΣ | 1..1 | CodeableConcept | What substance this is Binding: SubstanceCode (example): Substance codes. | ||||
| description |
Σ | 0..1 | string | Textual description of the substance, comments | ||||
| instance |
SΣ | 0..* | BackboneElement | If this describes a specific package/container of the substance | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations Constraints: ext-1 | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized Constraints: ext-1 | ||||
| identifier |
Σ | 0..1 | Identifier | Identifier of the package/container | ||||
| expiry |
Σ | 0..1 | dateTime | When no longer valid to use | ||||
| quantity |
SΣ | 0..1 | SimpleQuantity(4.0.1) | Amount of substance in the package | ||||
| ingredient |
SΣ | 0..* | BackboneElement | Composition information about the substance | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations Constraints: ext-1 | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized Constraints: ext-1 | ||||
| quantity |
SΣ | 0..1 | Ratio | Optional amount (concentration) | ||||
| Slices for substance[x] |
SΣ | 1..1 | A component of the substance Slice: Unordered, Open by type:$this Binding: SubstanceCode (example): Substance Ingredient codes. | |||||
| substanceCodeableConcept |
CodeableConcept | |||||||
| substanceReference |
Reference(Substance) | |||||||
| substance[x]:substanceReference |
SΣ | 0..1 | Reference(Atrius India Core Substance(0.1.0)) | A component of the substance | ||||
| Documentation for this format | ||||||||
Terminology Bindings
| Path | Status | Usage | ValueSet | Version | Source |
| Substance.language | Base | preferred | Common Languages | 📍4.0.1 | FHIR Std. |
| Substance.status | Base | required | FHIRSubstanceStatus | 📍4.0.1 | FHIR Std. |
| Substance.category | Base | extensible | Substance Category Codes | 📍4.0.1 | FHIR Std. |
| Substance.code | Base | example | Substance Code | 📍4.0.1 | FHIR Std. |
| Substance.ingredient.substance[x] | Base | example | Substance Code | 📍4.0.1 | FHIR Std. |
Constraints
| Id | Grade | Path(s) | Description | Expression |
| dom-2 | error | Substance | If the resource is contained in another resource, it SHALL NOT contain nested Resources |
contained.contained.empty()
|
| dom-3 | error | Substance | If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource |
contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
|
| dom-4 | error | Substance | If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated |
contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
|
| dom-5 | error | Substance | If a resource is contained in another resource, it SHALL NOT have a security label |
contained.meta.security.empty()
|
| dom-6 | best practice | Substance | A resource should have narrative for robust management |
text.`div`.exists()
|
| ele-1 | error | Substance.meta, Substance.implicitRules, Substance.language, Substance.text, Substance.extension, Substance.modifierExtension, Substance.identifier, Substance.status, Substance.category, Substance.code, Substance.description, Substance.instance, Substance.instance.extension, Substance.instance.modifierExtension, Substance.instance.identifier, Substance.instance.expiry, Substance.instance.quantity, Substance.ingredient, Substance.ingredient.extension, Substance.ingredient.modifierExtension, Substance.ingredient.quantity, Substance.ingredient.substance[x], Substance.ingredient.substance[x]:substanceReference | All FHIR elements must have a @value or children |
hasValue() or (children().count() > id.count())
|
| ext-1 | error | Substance.extension, Substance.modifierExtension, Substance.instance.extension, Substance.instance.modifierExtension, Substance.ingredient.extension, Substance.ingredient.modifierExtension | Must have either extensions or value[x], not both |
extension.exists() != value.exists()
|
Summary
Must-Support: 8 elements
Structures
This structure refers to these other structures:
Slices
This structure defines the following Slices:
- The element 1 is sliced based on the value of Substance.ingredient.substance[x]
Other representations of profile: CSV, Excel, Schematron